Project Description

Renal Tubular Acidosis (RTA): RTA is either a genetic or acquired disorder of the kidney, where the kidney cannot adequately eliminate H+ ions leading to a metabolic acidosis. RTA is often associated with kidney stone development due to associated high urine calcium or low urine citric acid excretion.

RTA is also associated with bone mineral deposition defects and osteomalacia. RTA can be effectively treated with either the addition of bicarbonate or citric acid, available in oral formulations.