Osteogenesis Imperfecta: Osteogenesis Imperfecta is a hereditary disorder of collagen formation. There are 4 forms of Osteogenesis Imperfecta, and, in adults, the dominant form, Type I, is accompanied by multiple fractures in long bones during childhood and adolescence, becoming less frequent with age.

Osteogenesis Imperfecta can be treated with intravenous bisphosphonates that reduce fracture risk.