Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis

Abaloparatide is a peptide that selectively binds to the RG conformation of the parathyroid hormone type 1 receptor. As a result of its mechanism of action, it was hypothesized that abaloparatide would have a more pronounced anabolic action on bone compared with teriparatide. The primary objective of this study was to determine the efficacy and adverse events of subcutaneous abaloparatide use compared with placebo for prevention of new vertebral fracture in postmenopausal women with osteoporosis….